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Seno Dwi Aribowo
"Perawat memiliki peran yang penting untuk mencegah pasien Intensive Care Unit yang terpasang ventilator agar tidak mengalami Ventilator Associated Pneumonia. Penelitian ini bertujuan untuk mengetahui gambaran tingkat pengetahuan perawat Intensive Care Unit terhadap pencegahan Ventilator Associated Pneumonia di RSUP Fatmawati Jakarta. Penelitian ini menggunakan metode cross sectional dengan analisis deskriptif pada 57 perawat Intensive Care Unit. Hasil dari penelitian ini menunjukkan bahwa tingkat pengetahuan perawat Intensive Care Unit RSUP Fatmawati berada dalam kategori sedang dengan persentase 74,04%. Penelitian ini menyarankan untuk perawat mengikuti pelatihan pencegahan Ventilator Associated Pneumonia sebagai upaya peningkatan pengetahuan dan penurunan angka kejadian Ventilator Associated Pneumonia di ruang Intensive Care Unit.

Nurses have important role to prevent Ventilator Associated Pneumonia in the mechanically ventilated patients in the Intensive Care Unit. This study aimed to described the level of knowledge of Intensive Care Unit nurses in the prevention of Ventilator Associated Pneumonia at RSUP Fatmawati Jakarta. This study used a cross sectional method with analytic descriptive to 57 nurses. The results of this study showed that the level of knowledge of Intensive Care Unit nurses at RSUP Fatmawati Jakarta are in the average-level with a percentage of 74.04%. This study suggested to following nursing training about Ventilator Associated Pneumonia prevention in order to increasing the knowledge level of Ventilator Associated Pneumonia prevention and as well as reducing the number of Ventilator Assoiated Pneumonia in the Intensive Care Unit."
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2016
S64595
UI - Skripsi Membership  Universitas Indonesia Library
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Muhammad Farhan Maruli
"Ventilator-associated pneumonia VAP punya prevalensi yang tinggi pada pasien pediatric intensive care unit PICU . Gizi lebih overweight dan obesitas dicurigai sebagai salah satu faktor risiko VAP namun hubungannya kurang diteliti. Penelitian ini bertujuan untuk menyelidiki hubungan antara gizi lebih dan kejadian VAP pada pasien PICU RSCM. Desain studi ini adalah cross-sectional analitik dengan data rekam medis pasien PICU RSCM yang mendapat ventilasi mekanik pada periode 2014 ndash;2016. Pasien dikatakan menderita gizi lebih berdasarkan assessment gizi pada rekam medis atau berdasarkan data antropometri dengan rujukan kriteria WHO atau CDC jika assessment gizi tidak ada. VAP ditentukan berdasarkan diagnosis tertulis pada rekam medis atau adanya gejala dan tanda yang memenuhi kriteria NNIS/CDC. Data tambahan yang diambil antara lain ada tidaknya kondisi immunocompromised, reintubasi, enteral feeding, penggunaan imunosupresan, antibiotik atau profilaksis stress ulcer. Sebanyak 64 pasien diikutsertakan sebagai subjek. Gizi lebih ditemukan pada 12 pasien 18.8 dan VAP pada 12 pasien 18.8 . Hanya satu pasien dengan gizi lebih mengalami VAP. Penelitian ini tidak menemukan hubungan antara gizi lebih dan kejadian VAP pada pasien PICU RSCM two-sided p = 0.436 dengan uji Fisher , mungkin karena sampel terlalu kecil. Penelitian prospektif dengan sampel yang cukup dibutuhkan untuk mengetahui hubungan antara gizi lebih dan VAP.

Ventilator associated pneumonia VAP is prevalent among pediatric intensive care unit PICU patients. Overnutrition overweight and obesity is a candidate for VAP risk factor but research into the link is wanting. This study aimed to investigate the association between overnutrition and VAP among PICU patients in RSCM. Medical records of RSCM PICU patients undergoing mechanical ventilation between 2014 and 2016 were used in this analytic cross sectional study. Overnutrition was established based on the nutritional assessment on the patient rsquo s medical record or anthropometric data using WHO or CDC criteria if the former was not available. VAP was established based on recorded diagnosis or the presence of signs and symptoms meeting the NNIS CDC criteria. Additional data include whether the patient was immunocompromised, reintubation, enteral feeding, use of immunosuppressants, antibiotics and stress ulcer prophylaxis. A total of 64 patients was included as subjects. Overnutrition was identified in 12 patients 18.8 and VAP in 12 patients 18.8 . Only one overnourished patient had VAP. This study found no association between overnutrition and VAP two sided p 0.436 by Fisher rsquo s test , probably because the sample was too small. Prospective studies with adequate sample sizes are needed to understand the link between overnutrition and VAP."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2017
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UI - Skripsi Membership  Universitas Indonesia Library
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Koe Stella Asadinia
"Latar belakang: Ventilator-associated pneumonia VAP merupakan jenis infeksi nosokomial terbanyak pada pasien pediatric intensive care unit PICU. VAP menyebabkan pemanjangan durasi ventilasi mekanik, durasi hospitalisasi, dan kematian. Omeprazole direkomendasikan sebagai profilaksis dan pengobatan stress ulcer pada pasien PICU dengan ventilator. Omeprazole diduga dapat meningkatkan kejadian VAP melalui peningkatan kolonisasi bakteri lambung. Namun, belum banyak studi yang meneliti pengaruh ini pada populasi pasien PICU.
Tujuan: Mengetahui pengaruh pemberian omeprazole terhadap kejadian VAP pada Pasien PICU di RSUPN Dr. Ciptomangunkusumo.
Metode: Studi ini dilaksanakan dengan metode cross-sectional dengan 58 subjek. Sampel diambil dari rekam medis pasien PICU tahun 2014 hingga 2016. Subjek terdiri dari dua kelompok, yaitu pasien PICU dengan ventilator yang diberi omeprazole dan tidak diberi omeprazole.
Hasil: Karakteristik subjek meliputi jenis kelamin, usia, status gizi, faktor risiko potensial, dan keluaran berupa durasi hospitalisasi, durasi intubasi, dan kematian. Sejumlah 9 dari 29-31 subjek yang diberi omeprazole mengalami VAP dan 3 dari 29-10 subjek yang tidak diberi omeprazole mengalami VAP. Uji Chi-square menunjukkan hubungan tidak bermakna antara omeprazole dan kejadian VAP dengan nilai p=0.105 dan prevalence ratio PR 3.00-95 CI 0.903-9.970.
Diskusi: Hasil penelitian ini menyatakan bahwa pemberian omeprazole tidak berpengaruh terhadap kejadian VAP pada pasien PICU.

Background: Ventilator associated pneumonia VAP is the most common nosocomial infection among pediatric intensive care unit PICU patients. VAP prolongs duration of intubation and hospitalization and increases mortality. Omeprazole is often used as prophylaxis and therapy for stress ulcer, a common disease in PICU patients. Omeprazole is suspected to increase VAP incidence through gastric colonization.
Aim: To determine the effect of omeprazole on incidence of ventilator associated pneumonia among RSUPN Dr. Ciptomangunkusumo PICU Patients.
Methods: This is a cross sectional study with 58 subjects obtained from PICU medical records from 2014 to 2016. Subjects were put into two categories 1 PICU patients who received omeprazole, and 2 PICU patients who did not receive omeprazole.
Results: Subject characteristics include sex, age, nutritional status, potential risk factors, and outcome duration of hospitalization, duration of intubation and mortality. A number of 9 of 29 31 patients who received omeprazole developed VAP and 3 of 29 10 patients who did not receive omeprazole developed VAP. Chi square test showed no significant difference in the incidence of VAP in the two categories p 0.105 and prevalence ratio PR 3.00 95 CI 0.903 9.970.
Discussion: Omeprazole does not affect the incidence of VAP on PICU patients in this study.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2017
S-Pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Sulthon Abdul Aziz
"Sistem pernapasan (respirasi) merupakan proses pertukaran gas oksigen (O2) yang dibutuhkan oleh tubuh untuk metabolisme sel dengan karbon dioksida (CO2) sebagai bentuk keluaran dari metabolisme. Gagal napas adalah ketidakmampuan sistem pernapasan dalam mempertahankan pemberian oksigen dalam darah dengan atau tanpa penumpukan karbon dioksida. Ventilator merupakan alat yang membantu dan menunjang pernapasan seseorang yang mengalami gagal napas. Ritme pernapasan yang diatur oleh mesin sering kali dirasakan tidak nyaman oleh pengguna dalam keadaan sadar sehingga diperlukan sinkronisasi antara ritme pengguna dengan mesin. Skripsi ini bertujuan untuk merancang ventilator mode Synchronized Intermittent Mandatory Ventilation (SIMV) yang tersinkronisasi dengan usaha napas pasien dengan berbagai nilai parameter tekanan pemicu. Mode SIMV ini dirancang dengan mikrokontroler STM32F411CEU6 sebagai pengontrol kerja komponen, sensor tekanan untuk mendeteksi usaha napas pasien, sensor aliran udara untuk mendeteksi aliran udara yang keluar. Masukan kepada alat ini adalah gas oksigen yang akan diolah dalam alat kemudian dikeluarkan sesuai dengan pemicu dari pasien dan volume yang diatur serta dalam pengujiannya digunakan ventilator analyzer dan paru-paru buatan. Hasil dari penelitian ini telah berhasil dilakukan rancang bangun ventilator mode SIMV dengan pembacaan Positive End Expiratory Pressure (PEEP) dan Peak Inspiratory Pressure (PIP), pembangkitan udara dengan usaha pasien sebanyak 20% dari nilai PEEP serta pembangkitan udara 300 ml, 400 ml, 500 ml, dan 600 ml dengan kesalahan pembacaan PEEP 0-16% dan PIP 0-9%, kesalahan perbandingan tekanan saat pembangkitan terhadap PEEP sebesar 0-9%, serta kesalahan luaran volume 0%-8%.

The respiratory system (respiration) is the process of exchanging oxygen gas (O2) needed by the body for cell metabolism with carbon dioxide (CO2) as a form of metabolism output. Respiratory failure is the inability of the respiratory system to maintain oxygen delivery in the blood with or without a buildup of carbon dioxide. Ventilator is a device that helps and supports the breathing of a person who has respiratory failure. The breathing rhythm regulated by the machine is often felt uncomfortable by the user in a conscious state so that synchronization between the user's rhythm and the machine is needed. This thesis aims to design a Synchronized Intermittent Mandatory Ventilation (SIMV) ventilator which is synchronized with the patient's respiratory effort with various trigger pressure parameter values. This SIMV mode is designed with STM32F411CEU6 microcontroller as a controller, pressure sensor to detect the patient's breath effort, an air flow sensor to detect the outgoing air flow. The input to this device is oxygen gas which will be processed in the device and then taken out according to the trigger from the patient and the volume is regulated, a ventilator analyzer and artificial lungs are used for testing the device. The results of this study have successfully carried out the design of the SIMV mode ventilator with Positive End Expiratory Pressure (PEEP) and Peak Inspiratory Pressure (PIP) readings, air generating with patient effort as much as 20% of the PEEP value and air generation of 300 ml, 400 ml, 500 ml, and 600 ml with PEEP reading errors of 0-16% and PIP 0-9%, the pressure ratio error when generating to PEEP is 0-9%, and the volume output error is 0%-8%."
Depok: Fakultas Teknik Universitas Indonesia, 2022
S-pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Rahmadius Eka Santoso
"Latar Belakang: Intensive care unit-acquired weakness (ICU-AW) adalah salah satu masalah yang dihadapi dalam manajemen pasien kritis karena dihubungkan dengan ventilasi mekanik berkepanjangan sehingga meningkatkan risiko komplikasi dan mortalitas selama di ICU. Mobilisasi dini seperti neuromuscular electrical stimulation (NMES) dilaporkan bermanfaat mengurangi durasi penggunaan ventilator di ICU. Telaah sistematik dan meta-analisis ini dibuat untuk menyimpulkan dampak dari NMES terhadap durasi penggunaan ventilator di ICU. Tujuan: Mengetahui dampak spesifik penggunaan NMES terhadap durasi penggunaan ventilator pada pasien ICU. Metode: Studi eligibel hingga Januari 2022 terinklusi dalam studi. Pencarian literatur dilakukan melalui database jurnal berbasis elektronik yaitu Cochrane, EBSCOHost, Scopus, dan Pubmed dengan kata kunci spesifik dan operator boolean. Studi terinklusi dievaluasi untuk risiko bias dengan Cochrane RoB 2 dan estimasi besar efek dilakukan dengan fixed effect model menggunakan perangkat lunak Review Manager 5.4. Hasil: Pencarian literatur menghasilkan 9 studi yang terinklusi dalam meta-analisis. Dari penggabungan data, disimpulkan bahwa penggunaan NMES berhubungan dengan penurunan durasi penggunaan ventilator (MD -1.48; 95% CI: -2,54 – -0,41, p = 0,007, I 2 =30%, fixed-effect modelling). Kesimpulan: Penelitian ini menyimpulkan bahwa pemberian NMES dapat menurunkan durasi penggunaan ventilator di ICU.

Background: Intensive Care Unit-Acquired Weakness (ICU-AW) is one of the problems faced in critical medicine management, associated with prolonged mechanical ventilation (PMV) thereby increasing risk and mortality while in the ICU. Early mobilization such as neuromuscular electrical stimulation (NMES) has been reported to be beneficial in reducing the duration of mechanical ventilation in the ICU. This systematic review and meta-analysis was conducted to conclude the impact of NMES on the duration of mechanical ventilation in the ICU. Objective: To determine the impact of the use of NMES on duration of mechanical ventilation in ICU patients. Methods: Eligible studies up to January 2022 were included in the study. The literature search was carried out through electronic-based journal databases, namely Cochrane, EBSCOHost, Scopus, and Pubmed with specific keywords and boolean operators. The included studies were evaluated for risk of bias with Cochrane RoB 2 and estimation of effect size was performed using a fixed effect modelling using Review Manager 5.4 software. Results: The literature search yielded 9 studies that were included in the meta- analysis. From the pooled data, it was concluded that NMES administration was associated with a decrease in the duration of mechanical ventilation (MD -1.48; 95% CI: -2.54 – -0.41, p = 0.007, I2 = 30%, fixed-effect modeling). Conclusion: This study concluded that the administration of NMES reduces the duration of ventilator use in the ICU."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Anti Dharmayanti
"A 46-year-old man was admitted to ICU with a diagnosis at the time of admission of Guillain Barre Syndrome (GBS) and sepsis due to suspected Ventilator-Associated Pneumoniae (VAP). Specimens for the following laboratory workup were inquired, i.e. complete blood count, culture and resistance workup using specimens obtained from the tip of suction pipe, urinalysis and urine culture, blood culture and resistance, procalcitonin and lactate levels. Neutrophilia was found along with increased procalcitonin and lactate levels, which supported the sepsis diagnosis. Moreover, the result of culture from suction pipe demonstrated colonies of Pseudomonas luteola MDRO, which might be originated from the oropharyngeal colonization of the patients due to poor oral hygiene and ineffective oral hygiene nursing; therefore, the colonies of the microorganism were swabbed away when obtaining the specimens. Ineffective oral hygiene nursing may have a potency to cause VAP and recurrent VAP."
Jakarta: Faculty of Medicine University of Indonesia, 2017
610 UI-IJIM 49: 2 (2017)
Artikel Jurnal  Universitas Indonesia Library
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