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Shabrina Narasati
"Salah satu tanaman herbal yang berkhasiat terhadap malaria adalah Sambiloto Andrographis panniculata Berm F Pada malaria terjadi peningkatan radikal bebas yang dapat merusak hati Penelitian ini bertujuan untuk mengetahui aktivitas hepatoprotektif sambiloto Andrographis paniculata Berm F terhadap mencit yang terinfeksi Plasmodium berghei secara in vivo Metode Mencit jantan galur Balb c dengan berat 28 30 g 7 8 minggu dibagi menjadi 4 kelompok secara acak dan tiap kelompok terdiri atas 5 ekor mencit Kelompok K kontrol Kelompok A kontrol negatif Kelompok B ekstrak Andrographis 2 mg kgBB 1 kali per hari selama7 hari dan kelompok C klorokuin 10 mg kgBB sekali sehari selama 3 hari Seluruh perlakuan diberikan melalui oral
Hasil Hasil penelitian memperlihatkan terdapat penurunan kadar aktivitas spesifik GPT pada hati yang diberi perlakuan ekstrak etanol sambiloto EES dibandingkan dengan kontrol negatif walaupun penurunan ini secara statistik tidak bermakna p ge 0 05 pada mencit yang diinfeksi Plasmodium berghei 5 8 1 6 vs 6 77 0 77 U mg protein jaringan hati Kesimpulan Berdasarkan hasil tersebut disimpulkan bahwa EES memiliki pengaruh terhadap penurunan kadar aktivitas spesifik GPT jaringan hati pada infeksi Plasmodium berghei namun pada dosis diperlukan dosis yang lebih tinggi untuk memperlihatkan hasil yang lebih bermakna.

Andrographis panniculata Berm F is a traditional herb used for the treatment of malaria Malaria infection can cause liver cell damage The aim of the study was to determine the hepatoprotective effect of an ethanolic extract of Andrographis panniculata Burm F EAA against Plasmodium berghei infected mice Methods Male mice Balb c strain weighing 28 30 g 7 8 weeks old were randomly divided into 4 groups of 5 animals each Group K controls nil Group A negative controls and 2 treatment groups B and C Group B Andrographis paniculatas 2 mg kgBW once per day for 4 days and group C Chloroquine 10 mg kgBW once a day for 3 days All treatments administrated orally
Results The results showed a decrease of GPT levels activity of the liver treated extract compared to negative controls in mice infected by Plasmodium berghei although the decrease was not statistically significant 5 8 1 6 vs 6 77 0 77 U mg protein of liver tissue p ge 0 05 Conclusion Based on these result it is concluded that the EES has an influence on the GPT activity by decreased it in Plasmodium berghei infected mice but the appropriate doses needed to show a more effective results.
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Jakarta: Fakultas Kedokteraan Universitas Indonesia, 2013
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UI - Skripsi Membership  Universitas Indonesia Library
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Irsalina Rahmawati
"Demam Berdarah Dengue DBD adalah penyakit infeksi yang ditularkan oleh nyamuk Aedes sp Angka Kejadian DBD di Kelurahan Cempaka Putih Barat tergolong tinggi sehingga perlu dilakukan pengendalian vektornya salah satunya dengan pemberantasan container tempat perkembangbiakan Aedes sp Jenis container dibagi menjadi dua yaitu TPA keperluan sehari hari dan TPA bukan keperluan sehari hari Penelitian ini merupakan studi cross sectional bertujuan mengetahui persebaran jenis container dan keberadaan larva Aedes sp pada berbagai jenis container di RW 03 dan RW 07 Kelurahan Cempaka Putih Barat yang memiliki karakteristik yang berbeda Pemukiman RW 03 adalah pemukiman yang tidak padat sedangkan RW 07 adalah pemukiman padat penduduk Data diambil menggunakan single larva method dan dianalisis menggunakan Chi Square Pada RW 03 didapatkan HI CI dan BI berturut turut 17 7 6 dan 23 dan 20 9 5 dan 22 di RW 07 Di RW 03 ditemukan 302 container dan di RW 07 ditemukan 230 container bak mandi merupakan jenis container terbanyak pada kedua RW Uji statistik menunjukkan tidak terdapat perbedaan bermakna antara keberadaan larva Aedes sp pada jenis container TPA keperluan sehari hari pada kedua RW p 0 321 dan terdapat perbedaan bermakna antara keberadaan larva Aedes sp pada jenis container TPA bukan keperluan sehari hari pada kedua RW p 0 006 Disimpulkan kepadatan dan penyebaran vektor DBD di RW 03 dan RW 07 Cempaka Putih Barat tinggi dan keberadaan larva Aedes sp berhubungan dengan jenis container TPA bukan keperluan sehari hari Kata kunci Cempaka Putih Barat container DBD larva Aedes sp RW 03 RW 07

Dengue Haemorrhagic Fever DHF is an infectious disease which is transmitted by Aedes sp Incidence of DHF in Kelurahan Cempaka Putih Barat is one of the highest so it is necessary to control vectors rsquo breeding place Container is divided into two types daily necessity container and non daily necessity container This cross sectional study aimed to identify the distribution of container and the presence of Aedes sp larvae on types of container in RW 03 and RW 07 which have different characteristic RW 03 is not densely populated residential different with RW 07 which is a densely populated residential The data was taken with single larval method and analyzed by Chi Square test In RW 03 House Index 17 Container Index 7 6 and Breteau Index 23 while in RW 07 House Index 20 Container Index 9 5 and Breteau Index 22 In this study there were 302 containers in RW 03 while in RW 07 there were 230 containers Tube is the most frequent container in RW 03 and RW 07 Statistically there were no significant difference between the presence of larvae with daily necessity container in RW 03 and RW 07 p 0 321 and there were significant difference between the presence of larvae with non daily necessity container in RW 03 and RW 07 p 0 006 In conclusion the distribution and density of DHF vector in RW 03 and RW 07 Kelurahan Cempaka Putih Barat are considered high and the presence of Aedes sp larvae is related with non daily necessity container Keywords Cempaka Putih Barat container DHF Aedes sp larvae RW 03 RW 07 "
Jakarta: Fakultas Kedokteraan Universitas Indonesia, 2013
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UI - Skripsi Membership  Universitas Indonesia Library
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Sari Mardiah
"Kasus Demam Berdarah Dengue DBD masih menjadi masalah kesehatan masyarakat di Indonesia salah satunya yaitu Jakarta Cempaka Putih merupakan salah satu zona merah kasus DBD yang terdapat di Jakarta Pusat Vektor penyakit DBD yaitu nyamuk Aedes sp dengan tempat perkembangbiakan terseringnya yaitu kontainer dalam rumah Penelitian ini dilakukan dengan metode cross sectional melalui survey larva secara single larval method terhadap kontainer dalam rumah di dua RW Kelurahan Cempaka Putih Barat dengan karakteristik pemukiman yang berbeda RW 03 memiliki karakteristik pemukiman menengah ke atas dengan jarak antar rumah yang cukup jauh dan RW 07 dengan karakter pemukiman menengah ke bawah dan jarak antar rumah yang dekat
Hasil penelitian menunjukkan jumlah kontainer dalam rumah pada RW 03 242 kontainer lebih banyak dari RW 07 199 kontainer dengan jenis kontainer terbanyak yaitu bak mandi di kedua RW tersebut Begitu juga dengan jumlah kontainer dalam rumah positif larva pada RW 03 delapan belas kontainer lebih banyak dari RW 07 empat belas kontainer dengan jenis kontainer dalam rumah positif larva terbanyak juga bak mandi Hasil uji kemaknaan Chi square p 0 86 menunjukkan keberadaan larva Aedes sp antara kedua RW tersebut tidak memiliki perbedaan bermakna Ini menunjukkan bahwa keberadaan larva tidak berhubungan dengan karakteristik pemukiman kedua RW tersebut.

Dengue Hemorragic Fever DHF is still be one of the public health problem in Indonesia especially in Jakarta Cempaka Putih is one of the red zone of DHF in Central Jakarta DHF is a vector borne disease carried by Aedes sp mosquitos as the vector the most dominant breeding place of which is in indoor containers This research was using cross sectional method to identify the distribution of indoor containers and the existence of Aedes sp larvae in two regions in Kelurahan Cempaka Putih Barat which have different characteristic of settlement The characteristic of RW 03 is upper middle class settlement with distance between houses are far enough and RW 07 consists of lower middle class settlement with distance between houses are quite close
The result of this research showed indoor containers found in RW 03 242 containers more than RW 07 199 containers with bathtub as the most frequent types of containers Also the indoor containers with positive larvae larvae were found in RW 03 eighteen containers more than in RW 07 fourteen containers with bathtub as the most frequent types of containers with positive larvae In conclusion based on the results of statistical tests p 0 86 the existence of Aedes sp larvae in indoor containers in the two regions is not significantly different It means that the existence of larvae was not related to the characteristics of the two regions
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Jakarta: Fakultas Kedokteraan Universitas Indonesia, 2013
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UI - Skripsi Membership  Universitas Indonesia Library
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Artasya Karnasih
"Demam Berdarah Dengue (DBD) adalah penyakit tular vektor oleh virus dengue dengan vektor Aedes sp. Cempaka Putih Barat tergolong salah satu kelurahan dengan jumlah kasus DBD yang tinggi, sehingga perlu dilakukan pengendalian vektor dengan memberantas tempat berkembangbiak nyamuk Aedes sp., yaitu container luar rumah. Penelitian ini dilakukan dengan tujuan mengetahui sebaran container luar rumah dan keberadaan larva Aedes sp di RW 03 dan RW 07 Kelurahan Cempaka Putih Barat. RW tersebut dipilih karena homogenitas karakteristik pemukiman, dimana RW 03 dihuni oleh rumah besar dengan jarak rumah yang lebar dan RW 07 dihuni oleh rumah kecil, padat dengan jarak rumah yang sempit. Penelitian menggunakan desain cross sectional dan survei larva menggunakan single larva method. Di RW 03 ditemukan enam puluh container luar rumah dengan empat belas jenis container dan terbanyak ember. Larva paling banyak ditemukan di tong. Di RW 07 ditemukan 31 container luar rumah dengan sepuluh jenis container dan terbanyak kolam/akuarium. Larva paling banyak ditemukan di drum dan kaleng bekas. Dengan demikian container luar rumah lebih banyak ditemukan di RW 03 tetapi berdasarkan uji statistik didapatkan container luar rumah positif larva lebih banyak di RW 07 (25,8%) daripada di RW 03 (8,3%) dengan (p=0,024), dapat disimpulkan terdapat perbedaan bermakna keberadaan larva Aedes sp. pada container luar rumah di RW 03 dan RW 07 Kelurahan Cempaka Putih Barat.

Dengue Hemorrhagic Fever (DHF) is a vector-borne disease by dengue virus and Aedes sp. as vector. West Cempaka Putih as one of district that the number of dengue cases are high. Therefore it is necessary to control the vector by eradicating potential breeding ground for Aedes sp. mosquitoes, container outside the house.The aim of study to identify the distribution of outdoor container and the presence of Aedes sp. larvae in RW 03 and RW 07 Cempaka Putih Barat. These was chose because homogenity of settlement characteristic that RW 03 is populated by people with big house and distance between houses are far. RW 07 is populated by people with small house and distance between houses are quite close. This study used cross sectional design and survey of larvae used single larvae method. In RW 03 was found sixty outdoor containers, fourteen types of container with most frequent container is bucket and larvae most commonly found in cans. In RW 07 was found thirty one outdoor containers, ten types of container with most frequent container is pond/aquarium and larvae most commonly found in the drums and tin cans. Thus the outdoor container is more commonly found in RW 03, but based on statistic test found that the number of containers with larvae in RW 07 (25,8%) is higher than in RW 03 (8.3%) with (p = 0.024). It can be concluded that there are significant differences in the existence of Aedes sp. larvae in the outdoor container between RW 03 and RW 07 West Cempaka Putih."
Jakarta: Fakultas Kedokteraan Universitas Indonesia, 2013
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UI - Skripsi Membership  Universitas Indonesia Library
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Theresia Rina Yunita
"ABSTRAK
Pendahuluan: Sambiloto atau Andrographis panniculata merupakan sebuah
tanaman herbal yang memiliki khasiat sebagai antimalaria dengan cara
meningkatkan kerja antioksidan dalam tubuh. Hati merupakan salah satu tempat
terjadinya fase perkembangan Plasmodium pada penyakit malaria. Penelitian ini
bertujuan untuk menganalisis aktivitas antimalaria dari Ekstrak Etanol Sambiloto
(EES) pada mencit yang diiinfeksi Plasmodium berghei secara in vivo melalu
pengukuran kadar MDA dan aktivitas spesifik katalase jaringan hati.
Metode: Desain penelitian yang digunakan adalah eksperimental in vivo
menggunakan hewan coba mencit Balb/c. Metode penelitian dilakukan dengan
mengelompokkan mencit ke dalam empat kelompok yaitu kelompok kontrol yang
tidak diberi perlakuan, kelompok I yang diinduksi Plasmodium berghei tetapi
tidak diterapi, kelompok II yang diinduksi Plasmodium berghei dan diberi EES 2
mg/kgBB serta kelompok III yang diinduksi Plasmodium berghei dan diberi
klorokuin 10 mg/kgBB selama 3 hari. Analisis kadar MDA dilakukan dengan
metode Wills dan aktivitas spesifik katalase dengan metode Mates et al.
Hasil: Hasil penelitian menunjukkan terjadi penurunan kadar MDA yang tidak
signifikan pada mencit yang diinfeksi dengan Plasmodium berghei dan diberi
ekstrak etanol sambiloto (EES) 2 mg/kgBB dibandingkan dengan kontrol negatif
(66.49 ± 22,92 vs 69.40 ± 11,69 nmol/g jaringan hati). Namun pada kelompok
yang diberi perlakuan klorokuin juga terlihat penurunan kadar MDA yang tidak
signifikan dibandingkan dengan kontrol negatif (67.49 ± 7,04 vs 69.40 ± 11,69
nmol/g jaringan hati). Sedangkan aktivitas spesifik katalase kelompok yang diberi
EES menunjukkan peningkatan yang tidak berbeda bermakna dibandingkan
dengan kelompok kontrol (2,73 ± 0,59 vs 3,73 ± 1.56 Unit/mg jaringan hati).
Begitupula dengan klorokuin yang menunjukkan peningkatan aktivitas spesifik
katalase yang tidak berbeda bermakna dibandingkan dengan kelompok kontrol
(2,97 ± 1,53 vs 3,73 ± 1.56).
Kesimpulan: Pada kelompok dengan pemberian EES 2 mg/kgBB terjadi
penurunan kadar MDA serta peningkatan aktivitas spesifik katalase jaringan hati
mencit dibandingkan dengan kelompok negatif, tetapi secara statistik tidak
bermakna demikian pula dengan kelompok yang diberi klorokuin.

ABSTRACT
Introduction: Andrographis panniculata or Sambiloto is a herbal plant that has
antimalarial efficacy by increasing antioxidant in body. Liver is one of the places
for Plasmodium to develop themselves in malaria. This research aims to analyze
the activity of antimalarial from Sambiloto Ethanol Extract (SEE) in mice which
infected by Plasmodium berghei in vivo through the measurement of MDA level
and the specific activity of catalase in liver tissue.
Method: We used experimental in vivo as the reserach design, using balb/c. The
research design is done by grouping the mices into four groups which of the
untreated group, group I-induced by Plasmodium berghei but not treated, group
II-induced Plasmodium berghei and treated with SEE 2 mg/kg Body weight,
group III-induced Plasmodium berghei and treated with chloroquine with 10
mg/kg Body weight in three days. The MDA level analyze is done by the Wills
method and the specific activity of catalase with Mates et al method.
Result: The research result showed the decrease of MDA level which not
significant in mice that is infected by Plasmodium berghei and treated by SEE 2
mg/ kg BW compared to negative control (66.49 ± 22,92 vs 69.40 ± 11,69 nmol/g
liver tissue). However, group that is infected by Plasmodium berghei and treated
by chloroquine also showed the decrease of MDA level which not significant
compared the negative control (67.49 ± 7,04 vs 69.40 ± 11,69 nmol/g liver tissue).
Instead, group which treated by SEE showed the increase in specific activity of
catalase compared with control (2,73 ± 0,59 vs 3,73 ± 1.56 Unit/mg liver tissue).
Similarly with chloroquine group which showed an increase in specific activity of
catalase were not significantly different compared with the control group (2.97 ±
1.53 vs 3.73 ± 1.56 Unit/mg liver tissue).
Conclusion: Group that treated with SEE 2 mg/kg Body weight showed decrease
of MDA level and also the increase of catalase specific activity in mice liver tissue
compared negative control, but statistically not significant as well as the group
given chloroquine;Introduction: Andrographis panniculata or Sambiloto is a herbal plant that has
antimalarial efficacy by increasing antioxidant in body. Liver is one of the places
for Plasmodium to develop themselves in malaria. This research aims to analyze
the activity of antimalarial from Sambiloto Ethanol Extract (SEE) in mice which
infected by Plasmodium berghei in vivo through the measurement of MDA level
and the specific activity of catalase in liver tissue.
Method: We used experimental in vivo as the reserach design, using balb/c. The
research design is done by grouping the mices into four groups which of the
untreated group, group I-induced by Plasmodium berghei but not treated, group
II-induced Plasmodium berghei and treated with SEE 2 mg/kg Body weight,
group III-induced Plasmodium berghei and treated with chloroquine with 10
mg/kg Body weight in three days. The MDA level analyze is done by the Wills
method and the specific activity of catalase with Mates et al method.
Result: The research result showed the decrease of MDA level which not
significant in mice that is infected by Plasmodium berghei and treated by SEE 2
mg/ kg BW compared to negative control (66.49 ± 22,92 vs 69.40 ± 11,69 nmol/g
liver tissue). However, group that is infected by Plasmodium berghei and treated
by chloroquine also showed the decrease of MDA level which not significant
compared the negative control (67.49 ± 7,04 vs 69.40 ± 11,69 nmol/g liver tissue).
Instead, group which treated by SEE showed the increase in specific activity of
catalase compared with control (2,73 ± 0,59 vs 3,73 ± 1.56 Unit/mg liver tissue).
Similarly with chloroquine group which showed an increase in specific activity of
catalase were not significantly different compared with the control group (2.97 ±
1.53 vs 3.73 ± 1.56 Unit/mg liver tissue).
Conclusion: Group that treated with SEE 2 mg/kg Body weight showed decrease
of MDA level and also the increase of catalase specific activity in mice liver tissue
compared negative control, but statistically not significant as well as the group
given chloroquine;Introduction: Andrographis panniculata or Sambiloto is a herbal plant that has
antimalarial efficacy by increasing antioxidant in body. Liver is one of the places
for Plasmodium to develop themselves in malaria. This research aims to analyze
the activity of antimalarial from Sambiloto Ethanol Extract (SEE) in mice which
infected by Plasmodium berghei in vivo through the measurement of MDA level
and the specific activity of catalase in liver tissue.
Method: We used experimental in vivo as the reserach design, using balb/c. The
research design is done by grouping the mices into four groups which of the
untreated group, group I-induced by Plasmodium berghei but not treated, group
II-induced Plasmodium berghei and treated with SEE 2 mg/kg Body weight,
group III-induced Plasmodium berghei and treated with chloroquine with 10
mg/kg Body weight in three days. The MDA level analyze is done by the Wills
method and the specific activity of catalase with Mates et al method.
Result: The research result showed the decrease of MDA level which not
significant in mice that is infected by Plasmodium berghei and treated by SEE 2
mg/ kg BW compared to negative control (66.49 ± 22,92 vs 69.40 ± 11,69 nmol/g
liver tissue). However, group that is infected by Plasmodium berghei and treated
by chloroquine also showed the decrease of MDA level which not significant
compared the negative control (67.49 ± 7,04 vs 69.40 ± 11,69 nmol/g liver tissue).
Instead, group which treated by SEE showed the increase in specific activity of
catalase compared with control (2,73 ± 0,59 vs 3,73 ± 1.56 Unit/mg liver tissue).
Similarly with chloroquine group which showed an increase in specific activity of
catalase were not significantly different compared with the control group (2.97 ±
1.53 vs 3.73 ± 1.56 Unit/mg liver tissue).
Conclusion: Group that treated with SEE 2 mg/kg Body weight showed decrease
of MDA level and also the increase of catalase specific activity in mice liver tissue
compared negative control, but statistically not significant as well as the group
given chloroquine"
Jakarta: Fakultas Kedokteraan Universitas Indonesia, 2013
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UI - Skripsi Membership  Universitas Indonesia Library
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Aryogi Rama Putra
"Latar belakang: Bayamduri (Amaranthus spinosus L.) adalah herbal tradisional yang digunakan untuk pengobatan malaria dan belum banyak data penelitian tentang ini. Penelitian ini bertujuan untuk mengetahui aktivitas skizontisidal ekstrak air bayam duri (Amaranthus spinosus L) (EABD) terhadap mencit yang diinfeksi Plasmodium berghei secara in vivo.
Metode: Mencit jantan (galur Balb/c) dengan berat 28-30 g, 7-8 minggu, dibagi menjadi 4 kelompok secara acak, tiap kelompok terdiri atas 5 ekor mencit. Kelompok K: kontrol, Kelompok A: kontrol negatif, 2 Kelompok perlakuan (B dan C). Kelompok B: ekstrak Amaranthus 120 mg/kgBB, 1 kali per hari selama 4 hari. dan kelompok C: klorokuin 10 mg/kgBB sekali sehari selama 3 hari. Seluruh perlakuan diberikan melalui oral.
Hasil: Aktivitas skizontisidal darah terlihat pada semua kelompok perlakuan (B dan C), Aktivitas tertinggi terlihat pada kelompok B yaitu 91,20 ± 0,73 %, sedang kelompok C sebesar 88,92 ± 1,10 %. Kedua kelompok berbeda secara bermakna dibandingkan dengan kontrol, p≤0,05, namun kedua kelompok tidak berbeda bermakna satu sama lain, p≥0,05. Terjadi peningkatan berat badan pada kelompok EABD yang hampir sama dengan kelompok kontrol dan lebih besar dibanding kelompok klorokuin (7,6 % vs 7,05% dan 5,48%).
Kesimpulan: Ekstrak air bayam duri (Amaranthus spinosus) (EABD) dosis 120 mg/kgBB menunjukkan aktivitas skizontisidal darah yang sama baik dengan pemberian klorokuin 10 mg/kgBB terhadap mencit yang diinfeksi Plasmodium berghei secara in vivo.

Background: Amaranthus spinosus is a traditional herb used for the treatment of malaria, but the information of it?s activity still limited. The aim of this study was to determine the schizonticidal effect of a water extract of Amaranthus spinosus against Plasmodium berghei-infected mice.
Methods: Male mice (Balb/c strain) weighing 28-30 g, 7-8 weeks old, were randomly devided into 4 groups of 5 animals each. Group K: controls (nil), Group A: negative controls, and 2 treatment groups (B and C). Group B: Amaranthus 120 mg/kgBW, once per day for 4 days and group C: Chloroquine 10 mg/kgBW, once a day for 3 days. All treatments administrated orally.
Results: Blood schizonticidal activity was seen in all treatment groups, the highest activity was seen in group B ( 91.20 ± 0.73%), and group C was 88.92 ± 1.10%. Both groups were significantly different compared to control, p≤0,05), but there were no different within both group. An increase in body weight in group B are almost the same as group K and greater than group C (7.6% vs 7.05% and 5.48%).
Conclusion: The Amaranthus spinosus water extract (ASWE) at a dose 120 mg/kgBW demonstrated a good blood schizonticidal activity as well as chloroquine against Plasmodium berghei-infected mice.
"
Jakarta: Fakultas Kedokteraan Universitas Indonesia, 2013
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UI - Skripsi Membership  Universitas Indonesia Library
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Fijri Auliyanti
"Latar belakang. Gangguan tidur pada remaja memiliki prevalens yang tinggi dan dapat memengaruhi prestasi akademik di sekolah. Namun, sejauh ini di Indonesia, belum terdapat studi yang meneliti prestasi akademik pada remaja dengan gangguan tidur serta faktor yang berhubungan.
Tujuan. Penelitian ini untuk mengetahui: (1) prevalens dan pola gangguan tidur berdasarkan SDSC, (2) proporsi murid SMP dengan gangguan tidur yang memiliki prestasi akademik di bawah rerata, (3) hubungan antara: jenis kelamin, motivasi dan strategi belajar, nilai IQ, tingkat pendidikan ibu, tingkat sosial ekonomi keluarga, struktur keluarga, pendidikan di luar sekolah, adanya TV/komputer di kamar tidur, durasi tidur di hari sekolah, perbedaan waktu tidur dan bangun, dan prestasi akademik murid SMP dengan gangguan tidur.
Metode. Penelitian potong lintang analitik di lima SMP di Jakarta pada bulan Januari hingga Maret 2013. Skrining gangguan tidur dengan kuesioner Sleep Disturbance Scale for Children dilakukan terhadap 491 orang murid SMP di Jakarta. Murid yang memenuhi kriteria gangguan tidur diminta mengisi kuesioner motivasi dan strategi pembelajaran. Peneliti meminta nilai IQ subjek penelitian.
Hasil. Terdapat 129 subjek yang memenuhi kriteria gangguan tidur. Empat orang subjek di drop-out karena tidak memiliki nilai IQ. Prevalens gangguan tidur sebesar 39,7% dengan jenis gangguan tidur terbanyak adalah gangguan memulai dan mempertahankan tidur (70,2%). Sebanyak 47,6% subjek memiliki prestasi akademik di bawah rerata. Sebagian besar subjek perempuan (71%), termasuk sosial ekonomi menengah ke bawah (58,9%), memiliki motivasi dan strategi belajar yang cukup (72,6%), dan mengikuti pendidikan di luar sekolah (87,9%). Tiga belas subjek yang memiliki nilai IQ di bawah rata-rata tidak diikutsertakan dalam analisis bivariat dan multivariat. Berdasarkan uji regresi logistik, faktor yang paling berhubungan dengan prestasi akademik di bawah rerata secara berurutan, yaitu pendidikan di luar sekolah (> 2 jenis, non-akademik), nilai IQ rata-rata, dan jenis kelamin lelaki.
Simpulan. Prevalens gangguan tidur pada murid SMP di Jakarta adalah 39,7% dengan jenis gangguan tidur terbanyak adalah gangguan memulai dan mempertahankan tidur. Sebanyak 47,6% subjek memiliki prestasi akademik di bawah rerata. Faktor yang terbukti berhubungan dengan prestasi akademik di bawah rerata adalah pendidikan di luar sekolah (> 2 jenis, non-akademik), nilai IQ rata-rata, dan jenis kelamin lelaki.

Background. Sleep disorders are prevalent in adolescents and may influence their academic achievement at school. However, in Indonesia, no research has ever been done to study academic achievement in students with sleep disorders and related factors.
Objectives. This study aimed to define: (1) the prevalence of sleep disorders and their patterns based on the SDSC questionnaire, (2) the proportion of junior high school students having low average academic achievement, (3) the relationship between factors; i.e gender, motivation and learning strategies, IQ level, mothers' educational level, socioeconomic level, family structure, non-formal education, TV/computer set inside the bedroom, sleep duration during schooldays, bedtimewakeup time difference; and the academic achievement in junior high school students with sleep disorders.
Method. This was an analytical cross-sectional study, performed at five junior high schools in Jakarta between January to March 2013. Screening for sleep disorders, based on the Sleep Disturbance Scale for Children questionnaires, was done in 491 junior high school students. Students who fulfilled the criteria of sleep disorders, were asked to fill in the Motivated Strategies for Learning Questionnaire (MSLQ). The IQ level of each subjects was also measured.
Results. There were 129 subjects who fulfilled the sleep disorders criteria. Four subjects were dropped out due to they didn?t have IQ level. The prevalence of sleep disorder in this study was 39.7%, mostly difficulty in initiating and maintaining sleep (70.2%). There were 47.6% subjects had low average academic achievement. As many as 13 subjects had low average IQ level and were not included in bivariate and multivariate analysis. Subjects mostly female (71%), with middle-low income (58.9%), had moderate motivation and learning strategies (72.6%), and attended non-formal education (87.9%). Based on the logistic regression analysis, the most influencing factors to the low average academic achievement are consecutively: the non-formal education ( > 2 types, non-academic), the average IQ level, and male sex.
Conclusion. The prevalence of sleep disorders in junior high school students in Jakarta are 39.7%, mostly difficulty in initiating and maintaining sleep. There were 47.6% subjects had low average grade. Factors related to the low average academic achievement are non-formal education ( > 2 types, non-academic), the average IQ level, and male sex.
"
Jakarta: Fakultas Kedokteraan Universitas Indonesia, 2013
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UI - Tesis Membership  Universitas Indonesia Library
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Ilum Anam
"Latar Belakang: Sindroma dispepsia sering dialami oleh penderita DM. Asam lambung salah satu faktor agresif terjadinya sindroma dispepsia dan tukak lambung. Penelitian ini bertujuan untuk mencari perbedaan pH lambung pada pasien dispepsia DM dengan yang bukan DM dan untuk mengetahui apakah ada korelasi antara pH lambung dengan proteinuria dan HbA1c.
Metode: Pasien terdiri dari 30 kelompok DM dan 30 kelompok bukan DM. Masing-masing kelompok dihitung pH lambung basal. pH lambung basal diukur dgn memasukkan elektroda kateter kedalam lambung selama 30 menit kemudian di rekam dgn alat PH Metri merek Digitrapper pH-Z. Beratnya komplikasi DM diukur dengan mikroalbuminuria, sedangkan kendali gula darah diukur dgn HbA1c. Dilakukan uji chi square utk mencari perbedaan pH lambung kelompok DM dgn yg bukan DM, dengan terlebih dahulu menentukan titik potong dgn analisa ROC (Receiver Operating Caracteristic). Dilakukan uji korelasi antara pH lambung basal dengan mikroalbuminuria dan HbA1c pada kelompok pasien DM.
Hasil: pH lambung basal pada dispepsia DM vs non DM (2.30±0.83 vs 2.19±0.52). Dgn uji chi square terdapat perbedaan bermakna antara kelompok DM dengan yang bukan DM. Pada uji korelasi antara pH lambung dengan mikroalbuminuria dijumpai r = 0.47 dan p < 0.05, sedangkan HbA1c dijumpai r=0,59 dan p > 0.05.
Simpulan: Ada perbedaan bermakna pH lambung basal antara pasien dispepsia DM dengan pasien dispepsia bukan DM. Ada korelasi antara pH lambung basal dengan mikroalbuminuria, sedangkan dengan HbA1c tidak ada korelasi. pH lambung basal pada pasien DM adalah 2.03±0.83 sedangkan pada yang bukan DM adalah 2.19±0.52.

Aims: Dyspepsia syndrome often experienced in diabetic patients. Gastric acid was one aggressive factors in dyspepsia syndrome. This aim of this study was to determine differences gastric pH between dyspepsia diabetic and dispepsia without diabetic patients. Also to determine whether there were a correlation between basal gastric pH and microalbuminuria and also HbA1c.
Methods: There were 30 patients diabetic and 30 patients without diabetic. Basal gastric pH was measured with an electrode catheter that inserted into the stomach for 30 minutes. Gastric pH will be recorded with PH Metri Digitrapper pH-Z. Diabetic complications measured by microalbuminuria, while the measured blood sugar control with HbA1c. Chi-square test to determine differences gastric pH between diabetic and without diabetic patients. Correlation test was performed between basal gastric pH and microalbuminuria and also HbA1c.
Results: We found basal gastric pH diabetic and non diabetic patients were (2.30±0.83 vs 2.19±0.52). There was significant differences between diabetic and non diabetic patients. From 30 diabeic patients we found a corelation between basal gastric pH and microalbuminuria (p < 0.05 and r = 0.47) and a no corelation with HbA1c (p > 0.05 and r=0,59).
Conclusions: There was significant differences basal gastric pH between diabetic and non diabetic patients. There was correlation between basal gastric pH and microalbuminuria, and no correlation with HbA1c. Basal gastric pH diabetic patients was 2,30 ± 0.83 and non diabetic patients was 2,19 ± 0,52.
"
Jakarta: Fakultas Kedokteraan Universitas Indonesia, 2013
T58556
UI - Tesis Membership  Universitas Indonesia Library
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Danti Filiadini
"Trikuriasis merupakan masalah kesehatan pada anak usia sekolah di Indonesia dengan prevalensi mencapai 56 3 Penyuluhan mengenai trikuriasis kepada anak usia sekolah sebagai upaya pencegahan perlu diberikan Penyuluhan sebaiknya disesuaikan dengan karakteristik demografi anak agar tepat sasaran Bantargebang merupakan lokasi tempat pembuangan sampah akhir dan pemukiman kumuh dengan sanitasi yang kurang baik sehingga berisiko tinggi terhadap trikuriasis Tujuan penelitian ini adalah untuk mengetahui hubungan tingkat pengetahuan mengenai T trichiura dengan karakteristik demografi murid SD X Bantargebang sebagai kelompok rentan Desain cross sectional digunakan dalam penelitian ini Pengambilan data dilakukan di SD X Bantargebang Bekasi pada tanggal 17 Desember 2011 dengan cara pengisian kuesioner yang terdiri atas 5 pertanyaan mengenai morfologi dan siklus hidup T trichiura Sampel penelitian adalah murid kelas 4 5 dan 6 SD X Bantargebang yang diambil dengan metode total sampling sebesar 58 responden Data diolah dengan program SPSS versi 20 dan dianalisis dengan uji Kolmogorov Smirnov Hasil penelitian menunjukkan bahwa 50 orang 86 2 memiliki pengetahuan rendah 8 orang 13 8 cukup dan tidak ada satu orang pun yang berpengetahuan baik 0 0 Tidak terdapat perbedaan bermakna antara tingkat pengetahuan dengan karakteristik demografi murid usia p 1 000 tingkat pendidikan p 1 000 info terdahulu p 1 000 dan jumlah sumber informasi p 0 999 Dapat disimpulkan bahwa tingkat pengetahuan tentang T trichiura tidak berhubungan dengan karakteristik demografi murid.

Trichuriasis has become a public health problem on school aged children in Indonesia with prevalence approximately 56 3 Health promotion needs to be given and associated with demographic characteristics of the students in order to achieve optimum result Bantargebang is a landfill and slum area with poor sanitation which is a risk factor for trichuriasis Therefore this study aims to determine the level of knowledge on T trichiura and its association with demographic characteristics of students in SD X Bantargebang Cross sectional design was used in this study The data was collected in SD X Bantargebang Bekasi on December 17th 2011 by distributing questionnaires which contain 5 questions about T trichiura Total sampling method of all 58 respondents was applied to pick out samples students of grade 4 5 and 6 in SD X The data was processed using SPSS program version 20 and analyzed with Kolmogorov Smirnov test The level of knowledge of 50 students 86 2 are categorized poor 8 students fair 13 8 and none of them 0 0 has good knowledge about T trichiura The analyzed data concludes that there is no significant difference between level of knowledge and demographic characteristics of students age p 1 000 level of education p 1 000 prior knowledge p 1 000 and the number of sources of information received p 0 999 As a conclusion level of knowledge about T trichiura is not related to demographic characteristics of students in SD X Bantargebang."
Jakarta: Fakultas Kedokteraan Universitas Indonesia, 2013
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UI - Skripsi Membership  Universitas Indonesia Library
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Lusi Tania Rahmartani
"Daerah Bantargebang merupakan daerah tempat pembuangan sampah terpadu TPST kumuh serta memiliki kepadatan penduduk yang cukup tinggi sehingga berisiko tinggi terjadinya askariasis Askariasis sering dialami oleh anak usia SD yaitu usia 7 12 tahun Untuk mencegah askariasis perlu dilakukan penyuluhan kepada murid SD Penelitian bertujuan mengetahui hubungan tingkat pengetahuan mengenai A lumbricoides dengan karakteristik demografi murid SD Agar tercapai tujuan penyuluhan optimal dibutuhkan penyesuaian dengan karakteristik demografinya Penelitian menggunakan desain cross sectional pada 58 murid SD X Bantargebang dengan metode total populasi Pengambilan data dilakukan pada tanggal 17 Desember 2011 dengan cara mengisi kuesioner yang berisi 5 pertanyaan tentang A lumbricoides Data dianalisis dengan uji Kolmogorov Smirnov dengan hasil perbandingan tingkat pengetahuan A lumbricoides dengan usia p 0 965 tingkat pendidikan p 0 610 sumber informasi p 1 000 dan info terdahulu p 1 000 Dari total 58 murid didapatkan murid yang memiliki pengetahuan kurang berjumlah 46 orang 79 3 cukup 10 orang 17 2 dan baik 2 orang 3 4 Dari analisis statistik didapatkan tidak ada perbedaan bermakna p 0 05 antara tingkat pengetahuan mengenai A lumbricoides dengan usia tingkat pendidikan info terdahulu dan sumber informasi Disimpulkan bahwa pengetahuan murid SD X mengenai A lumbricoides tergolong buruk dan tidak memiliki hubungan bermakna dengan karakterstik demografinya.

Ascariasis often experienced by children of primary school age group aged 7 12 years Bantargebang is an area that has a landfield area slump and has a high population so that Bantargebang have a high risk of ascariasis This can be prevented either by providing counseling as a health promotion In order to achieve the optimal goal counseling needs to be adjusted according to the characteristic This study aims to determine the relationship of student rsquo s knowledge about A lumbricoides with their demographic characteristics Studies using cross sectional design applied on 58 students X elemetary school Bantargebang with total population method Data collection was done on December 17th 2011 by filling questionnaires which contains 5 question about A lumbricoides Data processing was performed using SPSS version 20 0 analyzed by Kolmogorov Smirnov test with the result shows relationship between student rsquo s knowledge about A lumbricoides with their age p 0 965 level of education p 0 610 source of knowledge p 1 000 and prior knowledge p 1 000 The result shows students who have poor knowledge was 46 students 79 3 fair 10 students 17 2 and good 2 students 3 4 Based on Kolmogorov Smirnov test there is no significant difference p 0 05 between the level of knowledge about A lumbricoides with age level of education prior knowledge and source of knowledge It was concluded that students have poor knowlege about A lumbricoides and has no significant relationship with their demographic charateristics"
Depok: Fakultas Kedokteraan Universitas Indonesia, 2013
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UI - Skripsi Membership  Universitas Indonesia Library
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